What classes are best to take in high school if i want to become a dental hygienist?

- Chosen by Voters Try to get chemistry out of the way, you will probably have to retake it in college but at least you will have a feel for it. Talk to your counsler also and see what other classes you school has to offer, anatomy, chemistry, speech…etc. All of these will help.Good Luck Source(s): Dental Assistant 5 years ago 33% 4 Votes